Analysis of Correlation between Diet and Supplement Intake,and Early Age-Related Macular Degeneration

Kim, Jin Soo; Lee, Sang Moon; Yu, Hyeong Gon

Original Article

Korean Journal of Optometry and Vision Science 2014;13(1):9-13.
Published online June 30, 2014.

식습관 및 건강보조식품 섭취와초기 나이관련 황반변성의 상관관계 분석

김진수, 이상문, 유형곤

서울대학교 의과대학 서울대학교병원 안과학교실¹
서울대학교 의과대학 안과학교실2

Analysis of Correlation between Diet and Supplement Intake,and Early Age-Related Macular Degeneration

Jin Soo Kim, Sang Moon Lee, Hyeong Gon Yu

Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine1, Seoul, Korea
Department of Ophthalmology, Seoul National University College of Medicine2, Seoul, Korea

Abstract

Purpose
To investigate the relation of diet and supplement intake with the risk of early age-related macular degeneration (AMD)
in Koreans.
Methods: The medical records of 245 patients who visited healthcare center were retrospectively reviewed. Fundus photographs
were taken in all patients. Serum levels of vitamin D, total cholesterol, triglyceride, low-density lipoprotein (LDL) and high-density
lipoprotein (HDL) cholesterol and questionnaire about smoking and alcohol consumption status, diet and supplement intake
were collected.
Results: Twenty-five early AMD patients who were confirmed by fundus photography were compared with 220 patients without
AMD. Body mass index, serum cholesterol level, serum vitamin D level, smoking and alcohol consumption were not associated
with the risk of early AMD. Low sodium intake was associated with the risk of early AMD (OR = 4.295, CI 1.427-12.927). Other
diet and supplement intake were not associated with the risk of AMD.
Conclusions: Low sodium intake increased the risk of early AMD. Other diet or supplement intake was not associated with early
AMD.
(Korean J Optom Vis Sci 2014;13(1):9-13)

Key Words: Age-related macular degeneration, Diet, Sodium, Supplement